Eric Dier and Danny Rose return from injury for the Champions League game against CSKA Moscow on Tuesday night.
The England internationals missed the win over Middlesbrough at the weekend but have been declared fit for the trip to Russia. Pochettino will have to decide whether to risk the pair, particularly with Ben Davies and Wanyama capable replacements if needed.
We should know more later in the day when the Spurs squad flies out to Russia.